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ENT Case 9. Sinonasal tract content.
•Diagnosis: encephalocele •Congenital or iatrogenic •Clinical team usually knows the diagnosis before the surgery •Occasionally...
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Feb 7, 20241 min read
Cytopathology Case 1. Thyroid mass from an elderly patient.
cell block preparation: Diagnosis: metastatic lung adenocarcinoma to thyroid This case is challenging as the tumor cells demonstrating...
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Feb 6, 20241 min read
Cytopathology. Papillary thyroid carcinoma (PTC).
Nuclear features: Architectural features of PTC
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Feb 6, 20241 min read
ENT Case 7. Nasal cavity mass from a middle-aged male patient.
Diagnosis: Meningothelial meningioma Extracranial Sinonasal Tract Meningiomas etiology: –Direct extension from primary intracranial...
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Feb 5, 20241 min read
ENT Case 6. Laryngeal mass from a middle-aged male patient.
PITFALL to avoid: this is not medullary carcinoma of thyroid. Diagnosis: neurocrine tumor, grade 1 of larynx NET from larynx is rare and...
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Feb 5, 20241 min read
Bone and soft tissue Case 5. Thigh mass from a 4 YO patient.
The mass was biopsied and diagnosed at outside hospital as sarcoma. The patient was treated with chemoradiation, followed by amputation....
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Feb 3, 20241 min read
ENT case 5. Parotid mass from a 40 YO male patient
Multiple neck lymph nodes are positive for tumor: Next generation squence showed EWSR1-WT1 fusion. Diagnosis: Desmoplastic Small Round...
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Feb 3, 20241 min read
GYN Case 2. Hysterectomy from a young patient in 20s
•Diagnosis: epithelioid trophoblastic tumor
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Feb 2, 20241 min read
GYN Case 1. Endometrial curretage from a 40 year old patient.
•Diagnosis: epithelioid trophoblastic tumor (ETT) •ETT is a malignant neoplasm of chorionic-type intermediate trophoblast •The rarest of...
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Feb 2, 20241 min read
ENT case 4. Sinonasal mass from a middle-aged patient
Diffusely positive for both squamous and neuroendocrine markers. SMARCB1-deficient sinonasal carcinoma •Rare, high grade aggressive...
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Feb 1, 20241 min read
Bone and soft tissue Case 4. Lytic bone lesion from a pediatric patient.
•Diagnosis: Langerhans cell histiocytosis •Majority of cases have MAPK pathway gene mutations, with BRAFp.V600E being the most prevalent.
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Jan 31, 20241 min read
Bone and soft tissue Case 3. Painful knee mass from a middle-aged patient.
•Diagnosis: epithelioid hemangioendothelioma (EHE) •Great variability in clinical behavior and prognosis, occurs in patients of wide age...
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Jan 31, 20241 min read
Bone and soft tissue Case 2. Skull base mass from a 5 YO patient.
•Focal positivity for cytokeratin, brachyury, S100, SMA •INI1/SMARCB1 loss on immunohistochemical stain as well as SMARCB1 deletion on...
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Jan 31, 20241 min read
Bone and soft tissue case 1. Skull base mass.
•Diagnosis: chordoma •Clinical: most commonly presents as lytic, destructive bone lesion in the axial skeleton: base of the skull, spine,...
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Jan 31, 20241 min read
ENT case 3. Thyroid mass.
•Diagnosis: high grade follicular cell-derived non-anaplastic thyroid carcinoma, aka: poorly differentiated thyroid carcinoma •In the...
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Jan 31, 20241 min read
ENT case 2: buccal mucosa mass from a 19 YO patient
•Diagnosis: extraosseous/peripheral ameloblastoma •10% of all amelob;astomas, occur in wide age range 9-92 •Molecular changes: similar to...
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Jan 30, 20241 min read
ENT Case 1
•Diagnosis: Medullary carcinoma of thyroid •2% of thyroid malignancies, and 8% of thyroid cancer-related deaths •25% of MTCs are...
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Jan 30, 20241 min read
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