ENT case 2: buccal mucosa mass from a 19 YO patient

•Diagnosis: extraosseous/peripheral ameloblastoma

•10% of all amelob;astomas, occur in wide age range 9-92

•Molecular changes: similar to central ameloblastomas, MAPK signaling pathway mutation is common, with BRAFp.V600E being the most common mutation.

•Ddx: intraoral basal cell carcinoma and squamous cell carcinoma.

•Clinical: more indolent than conventional/central ameloblastoma, recurrence rate 9-20%